One Day TMS

ONE-D is an accelerated, physician-supervised TMS option that delivers 20 iTBS sessions in as little as one day.

Response Rates

81%

Depression

73%

Anxiety

64%

OCD

76%

PTSD

In 30 Seconds

ONE-D (Optimized Neuroplastogen-Enhanced Depression) treatment compresses a therapeutic course into one intensive treatment day - 20 iTBS sessions delivered under physician supervision.

It’s a time-efficient, emerging option, augmenting treatment response with the use of two medications: D-cycloserine and Vyvanse. It is offered as a self-pay program currently (Inspire’s all-in cost: $3,000).

What Is ONE-D (Single-Day TMS)?

Traditional TMS requires daily visits over many weeks - a significant barrier for people with work, family, or travel constraints. ONE-D addresses that barrier by delivering an intensive therapeutic treatment course in a single, tightly supervised day, while keeping the same safety and personalization steps used in standard and other accelerated TMS protocols. Early clinical reports and pilot data show encouraging response and remission rates (>70% response and near 50% remission) when conducted under careful clinical conditions.

How ONE-D works

  • iTBS format: ONE-D uses repeated blocks of intermittent Theta Burst Stimulation (iTBS). Each iTBS block is brief (as little as 3 minutes), but the full 20-session schedule builds a cumulative neuroplastic effect.


  • High density, short intervals:  Repeats many short sessions with short rest periods; the accumulated stimulation aims to produce a stronger, faster biological shift. 600 pulses of iTBS are delivered every 30 minutes in just one day.


  • Medication augmentation: Neuroplastogens (D-cycloserine and Vyvanse) are added the morning of treatments to enhance neuroplasticity — always under careful psychiatric supervision and informed consent.


  • Individualized mapping & monitoring: Motor-threshold mapping and personalized targeting based on updated scalp heuristics are used before the session so stimulation is safe and tailored to you.


How ONE-D compares to other options

Option Sessions Typical timing Insurance
Standard TMS 36+ 8 weeks Often covered
5-day Accelerated TMS 50 5 days (10/day) Self-pay ($7000)
ONE-D 20 1 Day Self-pay ($3,000)

Evidence & outcomes 

Several pilot and case-series on highly accelerated, neuroplastogen-enhanced protocols report high early response/remission rates (for example, single-day/accelerated protocols with up to ~90% response and ~74% remission rates at 6–12 weeks). These are promising early results; large randomized trials and longer-term follow-up remain an area of active study.


Accelerated protocols such as 50 sessions in 5 days (SAINT-style) have likewise demonstrated strong outcomes in trials and real-world clinic experience; ONE-D builds on that paradigm by intensifying delivery.

What to Expect

Psych history, med list, seizure risk check. (10–15 min consult available.)

Initial Consult & Screening

Done before treatment to personalize settings.

Mapping & Motor-Threshold

ONE-D treatment day(s)

Repeated brief iTBS sessions with staff monitoring; breaks provided.

PHQ-9 tracking and follow-up visits; touch-ups or maintenance plans discussed based on response.

Immediate & Scheduled Follow Up

Why Choose One-D?

Strong Results with Less Time Commitment

20 iTBS sessions in 1–2 days - many patients notice improvement within 2-6 weeks following treatment.


Physician-Supervised & Personalized

Planned and overseen by a TMS psychiatrist.


Ideal for Travelers & Time-Pressed Patients

Complete a full, physician-led course in a single trip.



Pros & Cons of One Day TMS

Pros

  • Limited time commitment - 20 iTBS sessions in 1–2 days.


  • Time-efficient - finish a full course in one trip.


  • Physician-supervised - mapped and overseen by a psychiatrist.

  • Non-invasive - outpatient, no anesthesia.

Cons

  • Insurance limits - self-pay for single-day formats.


  • Higher intensity - denser days result in no time for monitoring response over time or adjusting protocols.


  • Not for everyone - strict medical screening required.

Frequently Asked Questions

What is ONE-D (Single-Day TMS)?

ONE-D is an accelerated TMS option that delivers 20 iTBS sessions in as little as one day, intended as a time condensed therapeutic course. 

How Does ONE-D Work?

Who is a good candidate for ONE-D?

Are there any side effects of ONE-D?

How soon will I feel better after ONE-D?

How much does ONE-D cost and will insurance cover it?

How should I prepare for a ONE-D visit? What should I bring?

Not Sure Where to Start?

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Our shared inspiration is to alleviate mental illness and improve the mental wellbeing of the patients we treat. We respect all backgrounds and cultures and want to hear our patient’s stories to best guide care. During treatment, we reinforce positive wellness practices, help maximize lifestyle modifications, and integrate rTMS therapy into a patient’s overall mental and physical health treatment.


Samuel B. Clinch, M.D


Medical Director

Us vs Them

What sets Inspire TMS apart from typical TMS providers


Inspire TMS Denver

Sliding Scale Pricing Available

5-day Accelerated TMS Protocol

10–15 min call with Doctor

Focused Exclusively on TMS

>80% Clinic Response Rate

Cost Estimator Tool

15,000+ Treatments Completed


Other Clinics

Fixed Pricing Only

Often Unavailable

Long Wait or Intake Staff Only

Larger Multi-Service Clinics

Unpublished or National Data

No estimator or Guidance

Unknown Volume

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Making TMS Affordable For Everyone

We believe cost should never be a barrier to effective care. That’s why we offer:

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Sliding scale pricing for self-pay patients

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Coverage with most major insurance providers

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Free 10–15 minute consultation to get started

Why Choose Inspire TMS Denver

We combine clinical expertise with a personalized, patient-first approach. From board-certified care and flexible pricing to proven treatment outcomes, we’re here to help you find lasting relief - with support every step of the way.

Affordability Made Simple

Insurance, Financing & Sliding Scale Options

Board-Certified Psychiatrist

Over 10 Years of Clinical Experience

Fast-Track TMS Option

5-Day Protocol for Faster Relief

Proven Patient Outcomes

Success Rates Tracked In-Clinic

Free Doctor Consultation

No Obligation, 10–15 Minute Intro Call

Personalized Care Plans

Tailored TMS Treatment for Every Patient

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